Nutritional Perspectives

Nutritional Perspectives is a peer-reviewed journal that publishes original papers and review articles across the full range of nutritional science. The focus of all manuscripts submitted to the journal should be to increase knowledge in nutritional science relevant to human nutrition. Nutritional Perspectives welcomes manuscripts that report studies in nutritional epidemiology, nutritional requirements, metabolic studies, body composition, energetics, appetite and obesity. Manuscripts that address interactions of nutrition with endocrinology, genetics, immunology, microbiology, molecular and cell biology, neuroscience and physiology and that report outcomes relevant to health, behavior and well-being are also within scope for Nutritional Perspectives.


Periodic Fever Syndrome: A Case Study of Biofilm-Mediated Fever and Successful Treatment with Fibrinolytic Enzymes and Natural Antimicrobials

Periodic Fever Syndrome (PFS) is highlighted by a fever with or without additional symptoms. The underlying cause is suspected to be hereditary in nature from a genetic mutation. An underlying cause that is not commonly considered or diagnosed is a biofilm-related infection. A biofilm’s natural cycle of growth-release-repeat provides an episodic flow of microorganism into the body to cause a fever and the asymptomatic periods in-between typical in a PFS patient. The microorganisms being released can be bacterial, viral, fungal or a combination which triggers the periodic fevers while the biofilm acts as barrier hiding the infection from detection and drug therapies. A treatment protocol using fibrinolytic enzymes and a broad-spectrum antimicrobial may be an effective treatment for PFS not associated with a genetic mutation.

Steven Zodkoy, DC, CNS, DCBCN, DACBN

Bilateral Fibrocystic Breasts, Dysmenorrhea, and Anemia: A Case Report of Lugol’s Iodine & GLA Borage Oil

Bilateral Fibrocystic Breast is the most common form of benign breast disease and besides tender breasts is clinically associated with a relative risk for the subsequent development of cancer. We present a successful reversal of macrocytic anemia using iron bisglycinate, B-vitamins, and protein powder alongside symptomatic regression of bilateral fibrocystic breast with correction of concomitant mastodynia and dysmenorrhea using therapeutic iodine paired with estrogen metabolite support with GLA, DIM, I3C, and estrogen excretion with Calcium D-Glucarate.

Jennifer Gantzer, DC, MS, DACBN, FACN

Health Benefits of Polyphenols and Anthocyanins Found In Food

The complex polyphenol class of anthocyanins and polyphenols in general exhibit strong antioxidant properties in vitro. Plant foods and beverages derived from them contain polyphenols, one of the main antioxidants. Polyphenols appear to be beneficial to health based on the evidence in the literature. Their bioavailability and transport from the circulation to the target organs are required for their bioactivity in vivo. The effects of polyphenols and especially anthocyanins on antioxidant capacity have been relatively poorly studied to date. Various studies have shown that foods that contain polyphenols are associated with positive health outcomes due to their wide availability in a variety of foods that people consume on a daily basis. Finally, as a result of their capacity to enhance exercise recovery, anthocyanins (ACN), the sub-class of polyphenols responsible for the red, blue, and purple pigmentation of fruits and vegetables, have gained considerable interest in sport and exercise research.

Adrian Isaza, PhD, DC, MD, DABCI, DACBN, CCAP


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