A Metabolic Point of View on Parkinson’s Disease

In my newsletter series on inflammation, insulin resistance, and neurologic illness, while many neurodegenerative ailments were addressed, certainly the primary focus was Alzheimer’s disease. Others, such as Parkinson’s disease, were addressed, but not in nearly as much detail. In particular, given the incidence of Parkinson’s disease in the US, I feel it warrants more attention. Therefore, I was pleased to find a paper that addresses this ailment from a metabolic, allostatic load point of view, the recently published paper (February 2018) “Aging and Parkinson’s disease: Inflammaging, neuroinflammation and biological remodeling as key factors in pathogenesis” by Calabrese et al. The first quote I would like to feature from this paper discusses the significant frequency of Parkinson’s disease (PD):