Intravenous Magnesium as an Alternative to Long Acting Beta Agonists in Asthma Patients with Severe Acute Exacerbations. A Commentary on the Available Research

In 2010, Salpeter, et al, conducted a literature review that included 36,588 participants and found that long acting beta-agonists increased catastrophic events 2-fold. The review concluded that long-acting beta-agonists increase the risk for asthma-related intubations and deaths, even when used in a controlled fashion with concomitant inhaled corticosteroids.