Melatonin Deficiency Versus Delayed Secretion

There has been a lot of interest in the literature about the neuroprotective characteristics of melatonin, such as the ability of melatonin to reduce pyramidal neuronal death in the hippocampus, and this paper provides some insights and clinical approaches to manage two physiologically deficient states of melatonin secretion: overt melatonin deficiency versus Delayed Sleep Phase Syndrome (DSPS).