Under Appreciated Issues in the Treatment of Chronic Illness – Low Grade, Chronic Acidosis Combined With Potassium Deficiency – Part I

As we all know, it has become increasingly evident over the last few years that, more than any one single factor, the metabolic foundation of virtually every chronic illness chief complaint is chronic inflammation. Some compelling research is now making it clear that there is an intimate relationship between inflammation and metabolic acidosis.To introduce this concept, consider the following quote from the paper “Relationship between acid-base status and inflammation in the critically ill” by Zampieri et al: